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Chien-Fu Hung Selected Research

DNA Vaccines

9/2021Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine.
1/2021Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody.
5/2019Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines.
12/2018Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination.
1/2018Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice.
1/2018Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16+ Oral Tumors and Immunologic Control.
1/2018Intramuscular vaccination targeting mucosal tumor draining lymph node enhances integrins-mediated CD8+ T cell infiltration to control mucosal tumor growth.
1/2018Therapeutic DNA Vaccines for Human Papillomavirus and Associated Diseases.
12/2017Immunologic responses to a novel DNA vaccine targeting human papillomavirus-11 E6E7.
1/2017Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model.
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Chien-Fu Hung Research Topics

Disease

167Neoplasms (Cancer)
05/2022 - 03/2002
25Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 01/2007
25Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2021 - 01/2007
22Infections
12/2021 - 03/2003
20Papillomavirus Infections
01/2021 - 01/2003
9Communicable Diseases (Infectious Diseases)
01/2022 - 02/2003
9Vaccinia
01/2021 - 11/2002
5Hepatocellular Carcinoma (Hepatoma)
10/2018 - 03/2011
5Carcinogenesis
12/2013 - 07/2007
4Tuberculosis (Tuberculoses)
10/2021 - 11/2016
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2022 - 07/2017
3Leiomyoma (Uterine Fibroids)
03/2021 - 10/2003
3Melanoma (Melanoma, Malignant)
01/2021 - 02/2012
3Condylomata Acuminata (Genital Wart)
01/2021 - 11/2014
3Uterine Cervical Dysplasia
01/2021 - 02/2016
3Ascites
01/2020 - 07/2007
3Virus Diseases (Viral Diseases)
03/2010 - 09/2003
2Squamous Cell Carcinoma of Head and Neck
04/2022 - 01/2022
2Carcinoma (Carcinomatosis)
01/2022 - 01/2003
2Head and Neck Neoplasms (Head and Neck Cancer)
09/2021 - 12/2012
2Multiple Myeloma
01/2021 - 01/2015
2Renal Cell Carcinoma (Grawitz Tumor)
01/2021 - 02/2007
2Ovarian Epithelial Carcinoma
01/2018 - 12/2017
2Skin Neoplasms (Skin Cancer)
01/2018 - 07/2013
2Recurrent respiratory papillomatosis
01/2018 - 11/2010
2Papilloma (Papillomatosis)
01/2018 - 01/2017
2Inflammation (Inflammations)
09/2016 - 03/2015
2Hyperthermia
09/2015 - 01/2013
2Pancreatitis
03/2015 - 01/2009
2Necrosis
01/2014 - 03/2010

Drug/Important Bio-Agent (IBA)

67AntigensIBA
01/2022 - 03/2002
55DNA VaccinesIBA
09/2021 - 03/2002
53VaccinesIBA
01/2022 - 01/2003
47DNA (Deoxyribonucleic Acid)IBA
01/2022 - 03/2002
37Proteins (Proteins, Gene)FDA Link
01/2022 - 03/2002
24Therapeutic UsesIBA
01/2018 - 04/2007
23Papillomavirus Vaccines (HPV Vaccines)IBA
09/2021 - 01/2007
19Peptides (Polypeptides)IBA
01/2022 - 03/2003
16A-Form DNA (A-DNA)IBA
01/2021 - 05/2004
15Neoplasm Antigens (Tumor Antigens)IBA
01/2022 - 11/2002
12CalreticulinIBA
01/2020 - 08/2004
10Oncogene Proteins (Oncogene Protein)IBA
04/2021 - 07/2006
10Cisplatin (Platino)FDA LinkGeneric
01/2021 - 05/2008
9Pharmaceutical PreparationsIBA
01/2022 - 01/2007
9LuciferasesIBA
01/2020 - 07/2007
8EpitopesIBA
01/2022 - 03/2003
5LigandsIBA
01/2022 - 04/2009
5Proteasome Endopeptidase Complex (Proteasome)IBA
01/2021 - 01/2015
5MesothelinIBA
01/2018 - 01/2007
4HLA-A2 Antigen (HLA A2 Antigen)IBA
04/2022 - 01/2007
4Immune Checkpoint InhibitorsIBA
04/2021 - 12/2017
4Interleukin-2 (IL2)IBA
01/2021 - 12/2007
4Doxorubicin (Adriamycin)FDA LinkGeneric
01/2021 - 07/2010
4Bortezomib (Velcade)FDA Link
01/2021 - 08/2008
4UbiquitinIBA
01/2021 - 10/2016
4Paclitaxel (Taxol)FDA LinkGeneric
07/2014 - 01/2013
3TransposasesIBA
09/2021 - 01/2018
3Imiquimod (Aldara)FDA LinkGeneric
01/2021 - 04/2010
3Annexin A5IBA
01/2021 - 09/2016
3PiperidonesIBA
01/2021 - 10/2016
3RA190IBA
01/2021 - 10/2016
3Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2019
3Monoclonal AntibodiesIBA
01/2018 - 08/2008
3AntibodiesIBA
01/2018 - 08/2008
3CytokinesIBA
09/2016 - 07/2011
3Neutralizing AntibodiesIBA
01/2015 - 01/2007
3Tumor Viral Antigens (Large T Antigen)IBA
07/2013 - 10/2008
3Poly I-CIBA
08/2011 - 07/2004
3OvalbuminIBA
07/2011 - 07/2009
3HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
05/2009 - 10/2007
3Small Interfering RNA (siRNA)IBA
08/2008 - 01/2005
2Interferon Type IIBA
01/2022 - 12/2017
2Fumarate Hydratase (Fumarase)IBA
03/2021 - 02/2020
2Capsid Proteins (Capsid Protein)IBA
01/2021 - 01/2007
2InterleukinsIBA
01/2021 - 01/2013
2Isoniazid (Ftivazide)FDA LinkGeneric
01/2020 - 11/2016
2Anti-Bacterial Agents (Antibiotics)IBA
01/2020 - 11/2016
2Sorafenib (BAY 43-9006)FDA Link
10/2018 - 01/2018
2Immunoglobulin G (IgG)IBA
01/2018 - 02/2013
218 16 11 Types 6 Human Papillomavirus Recombinant Vaccine Quadrivalent (Gardasil)FDA Link
01/2018 - 12/2007
2ApigeninIBA
07/2017 - 05/2009
2Interferon-gamma (Interferon, gamma)IBA
07/2017 - 03/2002
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
03/2016 - 08/2008
2Histone Deacetylase InhibitorsIBA
01/2015 - 10/2013
2PlatinumIBA
05/2014 - 01/2013
2Fluorouracil (Carac)FDA LinkGeneric
03/2014 - 03/2011
2N-formylmethionylphenylalanine (FMP)IBA
03/2014 - 03/2011
2Mitoxantrone (Novantrone)FDA LinkGeneric
03/2014 - 03/2011
2AutoantigensIBA
01/2014 - 02/2013
2Histocompatibility Antigens Class IIBA
10/2013 - 07/2004
2Galactosylceramides (Galactocerebrosides)IBA
01/2013 - 10/2010

Therapy/Procedure

53Immunotherapy
01/2022 - 03/2002
34Therapeutics
01/2022 - 10/2003
20Drug Therapy (Chemotherapy)
01/2021 - 01/2007
9Investigational Therapies (Experimental Therapy)
07/2013 - 10/2007
7Radiotherapy
01/2018 - 05/2009
4Intraperitoneal Injections
05/2019 - 07/2007
2Hysterectomy
03/2021 - 02/2020
2Lasers (Laser)
09/2015 - 04/2009
2Combination Drug Therapy (Combination Chemotherapy)
03/2014 - 03/2011